Cargando…
Targeting Bruton’s Tyrosine Kinase in Inflammatory and Autoimmune Pathologies
Bruton’s tyrosine kinase (BTK) was discovered due to its importance in B cell development, and it has a critical role in signal transduction downstream of the B cell receptor (BCR). Targeting of BTK with small molecule inhibitors has proven to be efficacious in several B cell malignancies. Interesti...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8213343/ https://www.ncbi.nlm.nih.gov/pubmed/34150760 http://dx.doi.org/10.3389/fcell.2021.668131 |