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Targeting Bruton’s Tyrosine Kinase in Inflammatory and Autoimmune Pathologies

Bruton’s tyrosine kinase (BTK) was discovered due to its importance in B cell development, and it has a critical role in signal transduction downstream of the B cell receptor (BCR). Targeting of BTK with small molecule inhibitors has proven to be efficacious in several B cell malignancies. Interesti...

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Detalles Bibliográficos
Autores principales:	Neys, Stefan F. H., Hendriks, Rudi W., Corneth, Odilia B. J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8213343/ https://www.ncbi.nlm.nih.gov/pubmed/34150760 http://dx.doi.org/10.3389/fcell.2021.668131

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