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Epigenetic Features of HIV-Induced T-Cell Exhaustion Persist Despite Early Antiretroviral Therapy

T cell dysfunction occurs early following HIV infection, impacting the emergence of non-AIDS morbidities and limiting curative efforts. ART initiated during primary HIV infection (PHI) can reverse this dysfunction, but the extent of recovery is unknown. We studied 66 HIV-infected individuals treated...

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Detalles Bibliográficos
Autores principales: Martin, Genevieve E., Sen, Debattama R., Pace, Matthew, Robinson, Nicola, Meyerowitz, Jodi, Adland, Emily, Thornhill, John P., Jones, Mathew, Ogbe, Ane, Parolini, Lucia, Olejniczak, Natalia, Zacharopoulou, Panagiota, Brown, Helen, Willberg, Christian B., Nwokolo, Nneka, Fox, Julie, Fidler, Sarah, Haining, W. Nicholas, Frater, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8213372/
https://www.ncbi.nlm.nih.gov/pubmed/34149690
http://dx.doi.org/10.3389/fimmu.2021.647688