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Development of a Fluorescent Assay to Search New Drugs Using Stable tdTomato-Leishmania, and the Selection of Galangin as a Candidate With Anti-Leishmanial Activity

Antimonials continue to be considered the first-line treatment for leishmaniases, but its use entails a wide range of side effects and serious reactions. The search of new drugs requires the development of methods more sensitive and faster than the conventional ones. We developed and validated a flu...

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Detalles Bibliográficos
Autores principales: García-Bustos, María Fernanda, Moya Álvarez, Agustín, Pérez Brandan, Cecilia, Parodi, Cecilia, Sosa, Andrea Mabel, Buttazzoni Zuñiga, Valeria Carolina, Pastrana, Oscar Marcelo, Manghera, Paula, Peñalva, Pablo Alejandro, Marco, Jorge Diego, Barroso, Paola Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8213385/
https://www.ncbi.nlm.nih.gov/pubmed/34150675
http://dx.doi.org/10.3389/fcimb.2021.666746