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NEC-like intestinal injury is ameliorated by Lactobacillus rhamnosus GG in parallel with SIGIRR and A20 induction in neonatal mice

BACKGROUND: Exaggerated Toll-like receptor (TLR) signaling and intestinal dysbiosis are key contributors to necrotizing enterocolitis (NEC). Lactobacillus rhamnosus GG (LGG) decreases NEC in preterm infants, but underlying mechanisms of protection remain poorly understood. We hypothesized that LGG a...

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Detalles Bibliográficos
Autores principales: Cuna, Alain, Yu, Wei, Menden, Heather, Feng, Linda, Srinivasan, Pugazhendhi, Chavez-Bueno, Susana, Ahmed, Ishfaq, Umar, Shahid, Sampath, Venkatesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8213439/
https://www.ncbi.nlm.nih.gov/pubmed/32053825
http://dx.doi.org/10.1038/s41390-020-0797-6