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LDHA-Mediated Glycolytic Metabolism in Nucleus Pulposus Cells Is a Potential Therapeutic Target for Intervertebral Disc Degeneration

The intervertebral disc degeneration (IDD) is considered to be an initiator of a series of spinal diseases, among which changes in the nucleus pulposus (NP) are the most significant. NP cells reside in a microenvironment with a lack of blood vessels, hypoxia, and low glucose within the intervertebra...

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Detalles Bibliográficos
Autores principales: Wu, Longxi, Shen, Jieliang, Zhang, Xiaojun, Hu, Zhenming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8213459/
https://www.ncbi.nlm.nih.gov/pubmed/34222486
http://dx.doi.org/10.1155/2021/9914417