Simultaneous Brg1 Knockout and MYCN Overexpression in Cerebellar Granule Neuron Precursors Is Insufficient to Drive Tumor Formation but Temporarily Enhances their Proliferation and Delays their Migration

Medulloblastoma (MB) is the most common malignant brain tumor in childhood. According to the World Health Organization (WHO) classification of central nervous system (CNS) tumors, this embryonal tumor is divided into a wingless (WNT)-activated, Sonic hedgehog (SHH)-activated, and non-WNT/non-SHH ent...

Descripción completa

Detalles Bibliográficos
Autores principales: Holdhof, Dörthe, On, Ji Hoon, Schoof, Melanie, Göbel, Carolin, Schüller, Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8213679/
https://www.ncbi.nlm.nih.gov/pubmed/33387268
http://dx.doi.org/10.1007/s12311-020-01219-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8213679/
https://www.ncbi.nlm.nih.gov/pubmed/33387268
http://dx.doi.org/10.1007/s12311-020-01219-2

Ejemplares similares