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Enantioselective synthesis of tertiary boronic esters through catalytic asymmetric reversed hydroboration

Chiral tertiary boronic esters are important precursors to bioactive compounds and versatile synthetic intermediates to molecules containing quaternary stereocenters. The development of conjugate boryl addition to α,β-unsaturated amide has been hampered by the intrinsic low electrophilicity of the a...

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Detalles Bibliográficos
Autores principales: Gao, Tao-Tao, Lu, Hou-Xiang, Gao, Peng-Chao, Li, Bi-Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8213697/
https://www.ncbi.nlm.nih.gov/pubmed/34145273
http://dx.doi.org/10.1038/s41467-021-24012-z