Circular RNA AFF4 modulates osteogenic differentiation in BM-MSCs by activating SMAD1/5 pathway through miR-135a-5p/FNDC5/Irisin axis

Bone marrow-derived mesenchymal stem cells (BM-MSCs), the common progenitor cells of adipocytes and osteoblasts, have been recognized as the key mediator during bone formation. Herein, our study aim to investigate molecular mechanisms underlying circular RNA (circRNA) AFF4 (circ_AFF4)-regulated BM-M...

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Detalles Bibliográficos
Autores principales: Liu, Chao, Liu, An-Song, Zhong, Da, Wang, Cheng-Gong, Yu, Mi, Zhang, Hao-Wei, Xiao, Han, Liu, Jian-Hua, Zhang, Jian, Yin, Ke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8213698/
https://www.ncbi.nlm.nih.gov/pubmed/34145212
http://dx.doi.org/10.1038/s41419-021-03877-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8213698/
https://www.ncbi.nlm.nih.gov/pubmed/34145212
http://dx.doi.org/10.1038/s41419-021-03877-4

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