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Neonatal administration of a subanaesthetic dose of JM-1232(−) in mice results in no behavioural deficits in adulthood

In animal models, neonatal exposure of general anaesthetics significantly increases apoptosis in the brain, resulting in persistent behavioural deficits later in adulthood. Consequently, there is growing concern about the use of general anaesthetics in obstetric and paediatric practice. JM-1232(−) h...

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Detalles Bibliográficos
Autores principales: Iwanaga, Koji, Satoh, Yasushi, Akai, Ryosuke, Ishizuka, Toshiaki, Kazama, Tomiei, Ikeda, Takehiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8213711/
https://www.ncbi.nlm.nih.gov/pubmed/34145371
http://dx.doi.org/10.1038/s41598-021-92344-3