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Neonatal administration of a subanaesthetic dose of JM-1232(−) in mice results in no behavioural deficits in adulthood
In animal models, neonatal exposure of general anaesthetics significantly increases apoptosis in the brain, resulting in persistent behavioural deficits later in adulthood. Consequently, there is growing concern about the use of general anaesthetics in obstetric and paediatric practice. JM-1232(−) h...
Autores principales: | Iwanaga, Koji, Satoh, Yasushi, Akai, Ryosuke, Ishizuka, Toshiaki, Kazama, Tomiei, Ikeda, Takehiko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8213711/ https://www.ncbi.nlm.nih.gov/pubmed/34145371 http://dx.doi.org/10.1038/s41598-021-92344-3 |
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