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Messenger RNA expressing PfCSP induces functional, protective immune responses against malaria in mice

Human malaria affects the vast majority of the world’s population with the Plasmodium falciparum species causing the highest rates of morbidity and mortality. With no licensed vaccine and leading candidates achieving suboptimal protection in the field, the need for an effective immunoprophylactic op...

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Detalles Bibliográficos
Autores principales: Mallory, Katherine L., Taylor, Justin A., Zou, Xiaoyan, Waghela, Ishita N., Schneider, Cosette G., Sibilo, Michael Q., Punde, Neeraja M., Perazzo, Leah C., Savransky, Tatyana, Sedegah, Martha, Dutta, Sheetij, Janse, Chris J., Pardi, Norbert, Lin, Paulo J. C., Tam, Ying K., Weissman, Drew, Angov, Evelina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8213722/
https://www.ncbi.nlm.nih.gov/pubmed/34145286
http://dx.doi.org/10.1038/s41541-021-00345-0