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Hakai is required for stabilization of core components of the m(6)A mRNA methylation machinery

N(6)-methyladenosine (m(6)A) is the most abundant internal modification on mRNA which influences most steps of mRNA metabolism and is involved in several biological functions. The E3 ubiquitin ligase Hakai was previously found in complex with components of the m(6)A methylation machinery in plants a...

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Detalles Bibliográficos
Autores principales: Bawankar, Praveen, Lence, Tina, Paolantoni, Chiara, Haussmann, Irmgard U., Kazlauskiene, Migle, Jacob, Dominik, Heidelberger, Jan B., Richter, Florian M., Nallasivan, Mohanakarthik P., Morin, Violeta, Kreim, Nastasja, Beli, Petra, Helm, Mark, Jinek, Martin, Soller, Matthias, Roignant, Jean-Yves
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8213727/
https://www.ncbi.nlm.nih.gov/pubmed/34145251
http://dx.doi.org/10.1038/s41467-021-23892-5