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Hakai is required for stabilization of core components of the m(6)A mRNA methylation machinery
N(6)-methyladenosine (m(6)A) is the most abundant internal modification on mRNA which influences most steps of mRNA metabolism and is involved in several biological functions. The E3 ubiquitin ligase Hakai was previously found in complex with components of the m(6)A methylation machinery in plants a...
Autores principales: | Bawankar, Praveen, Lence, Tina, Paolantoni, Chiara, Haussmann, Irmgard U., Kazlauskiene, Migle, Jacob, Dominik, Heidelberger, Jan B., Richter, Florian M., Nallasivan, Mohanakarthik P., Morin, Violeta, Kreim, Nastasja, Beli, Petra, Helm, Mark, Jinek, Martin, Soller, Matthias, Roignant, Jean-Yves |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8213727/ https://www.ncbi.nlm.nih.gov/pubmed/34145251 http://dx.doi.org/10.1038/s41467-021-23892-5 |
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