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Inhibition of discoidin domain receptors by imatinib prevented pancreatic fibrosis demonstrated in experimental chronic pancreatitis model

Discoidin domain receptors (DDR1 and DDR2) are the collagen receptors of the family tyrosine kinases, which play significant role in the diseases like inflammation, fibrosis and cancer. Chronic pancreatitis (CP) is a fibro-inflammatory disease in which recurrent pancreatic inflammation leads to panc...

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Detalles Bibliográficos
Autores principales: Bansod, Sapana, Saifi, Mohd Aslam, Godugu, Chandraiah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8213731/
https://www.ncbi.nlm.nih.gov/pubmed/34145346
http://dx.doi.org/10.1038/s41598-021-92461-z