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Establishment and characterization of immortalized human breast cancer cell lines from breast cancer patient-derived xenografts (PDX)

The application of patient-derived xenografts (PDX) in drug screening and testing is a costly and time-consuming endeavor. While cell lines permit extensive mechanistic studies, many human breast cancer cell lines lack patient characteristics and clinical treatment information. Establishing cell lin...

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Detalles Bibliográficos
Autores principales: Zhuang, Yongxian, Grainger, Jordan M., Vedell, Peter T., Yu, Jia, Moyer, Ann M., Gao, Huanyao, Fan, Xiao-Yang, Qin, Sisi, Liu, Duan, Kalari, Krishna R., Goetz, Matthew P., Boughey, Judy C., Weinshilboum, Richard M., Wang, Liewei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8213738/
https://www.ncbi.nlm.nih.gov/pubmed/34145270
http://dx.doi.org/10.1038/s41523-021-00285-x