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Establishment and characterization of immortalized human breast cancer cell lines from breast cancer patient-derived xenografts (PDX)
The application of patient-derived xenografts (PDX) in drug screening and testing is a costly and time-consuming endeavor. While cell lines permit extensive mechanistic studies, many human breast cancer cell lines lack patient characteristics and clinical treatment information. Establishing cell lin...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8213738/ https://www.ncbi.nlm.nih.gov/pubmed/34145270 http://dx.doi.org/10.1038/s41523-021-00285-x |