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Multi-omics profiling of primary small cell carcinoma of the esophagus reveals RB1 disruption and additional molecular subtypes

Primary small cell carcinoma of the esophagus (PSCCE) is a lethal neuroendocrine carcinoma. Previous studies proposed a genetic similarity between PSCCE and esophageal squamous cell carcinoma (ESCC) but provided little evidence for differences in clinical course and neuroendocrine differentiation. W...

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Detalles Bibliográficos
Autores principales: Li, Renda, Yang, Zhenlin, Shao, Fei, Cheng, Hong, Wen, Yaru, Sun, Sijin, Guo, Wei, Li, Zitong, Zhang, Fan, Xue, Liyan, Bi, Nan, Wang, Jie, Sun, Yingli, Li, Yin, Tan, Fengwei, Xue, Qi, Gao, Shugeng, Shi, Susheng, Gao, Yibo, He, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8213753/
https://www.ncbi.nlm.nih.gov/pubmed/34145257
http://dx.doi.org/10.1038/s41467-021-24043-6