Comparison of microsatellite instability detection by immunohistochemistry and molecular techniques in colorectal and endometrial cancer

DNA mismatch repair deficiency (dMMR) testing is crucial for diagnosing Lynch syndrome and detection of microsatellite unstable (MSI) tumors eligible for immunotherapy. The aim of this study was to compare the relative diagnostic performance of three molecular MSI assays: polymerase chain reaction (...

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Detalles Bibliográficos
Autores principales: Dedeurwaerdere, Franceska, Claes, Kathleen BM, Van Dorpe, Jo, Rottiers, Isabelle, Van der Meulen, Joni, Breyne, Joke, Swaerts, Koen, Martens, Geert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8213758/
https://www.ncbi.nlm.nih.gov/pubmed/34145315
http://dx.doi.org/10.1038/s41598-021-91974-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8213758/
https://www.ncbi.nlm.nih.gov/pubmed/34145315
http://dx.doi.org/10.1038/s41598-021-91974-x

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