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Comparison of microsatellite instability detection by immunohistochemistry and molecular techniques in colorectal and endometrial cancer
DNA mismatch repair deficiency (dMMR) testing is crucial for diagnosing Lynch syndrome and detection of microsatellite unstable (MSI) tumors eligible for immunotherapy. The aim of this study was to compare the relative diagnostic performance of three molecular MSI assays: polymerase chain reaction (...
Autores principales: | Dedeurwaerdere, Franceska, Claes, Kathleen BM, Van Dorpe, Jo, Rottiers, Isabelle, Van der Meulen, Joni, Breyne, Joke, Swaerts, Koen, Martens, Geert |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8213758/ https://www.ncbi.nlm.nih.gov/pubmed/34145315 http://dx.doi.org/10.1038/s41598-021-91974-x |
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