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Serum amyloid P component is an essential element of resistance against Aspergillus fumigatus

Serum amyloid P component (SAP, also known as Pentraxin 2; APCS gene) is a component of the humoral arm of innate immunity involved in resistance to bacterial infection and regulation of tissue remodeling. Here we investigate the role of SAP in antifungal resistance. Apcs(−/−) mice show enhanced sus...

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Detalles Bibliográficos
Autores principales: Doni, Andrea, Parente, Raffaella, Laface, Ilaria, Magrini, Elena, Cunha, Cristina, Colombo, Federico Simone, Lacerda, João F., Campos, António, Mapelli, Sarah N., Petroni, Francesca, Porte, Rémi, Schorn, Tilo, Inforzato, Antonio, Mercier, Toine, Lagrou, Katrien, Maertens, Johan, Lambris, John D., Bottazzi, Barbara, Garlanda, Cecilia, Botto, Marina, Carvalho, Agostinho, Mantovani, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8213769/
https://www.ncbi.nlm.nih.gov/pubmed/34145258
http://dx.doi.org/10.1038/s41467-021-24021-y