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In silico investigation of pro-arrhythmic effects of azithromycin on the human ventricle

The macrolide antibiotic azithromycin (AZM) is widely used for respiratory infections and has been suggested to be a possible treatment for the Coronavirus Disease of 2019 (COVID-19). However, AZM-associated QT interval prolongation and arrhythmias have been reported. Integrated mechanistic informat...

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Detalles Bibliográficos
Autores principales: Liu, Yizhou, Zhang, Rai, Hancox, Jules C., Zhang, Henggui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8213892/
https://www.ncbi.nlm.nih.gov/pubmed/34179514
http://dx.doi.org/10.1016/j.bbrep.2021.101043