A novel CRISPR-based malaria diagnostic capable of Plasmodium detection, species differentiation, and drug-resistance genotyping

BACKGROUND: CRISPR-based diagnostics are a new class of highly sensitive and specific assays with multiple applications in infectious disease diagnosis. SHERLOCK, or Specific High-Sensitivity Enzymatic Reporter UnLOCKing, is one such CRISPR-based diagnostic that combines recombinase polymerase pre-a...

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Detalles Bibliográficos
Autores principales: Cunningham, Clark H., Hennelly, Christopher M., Lin, Jessica T., Ubalee, Ratawan, Boyce, Ross M., Mulogo, Edgar M., Hathaway, Nicholas, Thwai, Kyaw L., Phanzu, Fernandine, Kalonji, Albert, Mwandagalirwa, Kashamuka, Tshefu, Antoinette, Juliano, Jonathan J., Parr, Jonathan B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8213918/
https://www.ncbi.nlm.nih.gov/pubmed/34139428
http://dx.doi.org/10.1016/j.ebiom.2021.103415

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8213918/
https://www.ncbi.nlm.nih.gov/pubmed/34139428
http://dx.doi.org/10.1016/j.ebiom.2021.103415

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