Cargando…

A novel CRISPR-based malaria diagnostic capable of Plasmodium detection, species differentiation, and drug-resistance genotyping

BACKGROUND: CRISPR-based diagnostics are a new class of highly sensitive and specific assays with multiple applications in infectious disease diagnosis. SHERLOCK, or Specific High-Sensitivity Enzymatic Reporter UnLOCKing, is one such CRISPR-based diagnostic that combines recombinase polymerase pre-a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cunningham, Clark H., Hennelly, Christopher M., Lin, Jessica T., Ubalee, Ratawan, Boyce, Ross M., Mulogo, Edgar M., Hathaway, Nicholas, Thwai, Kyaw L., Phanzu, Fernandine, Kalonji, Albert, Mwandagalirwa, Kashamuka, Tshefu, Antoinette, Juliano, Jonathan J., Parr, Jonathan B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Research paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8213918/ https://www.ncbi.nlm.nih.gov/pubmed/34139428 http://dx.doi.org/10.1016/j.ebiom.2021.103415

Ejemplares similares

A novel duplex qualitative real-time PCR assay for the detection and differentiation of Plasmodium ovale curtisi and Plasmodium ovale wallikeri malaria
por: He, Wenqiao, et al.
Publicado: (2023)

Analysis of false-negative rapid diagnostic tests for symptomatic malaria in the Democratic Republic of the Congo
por: Parr, Jonathan B., et al.
Publicado: (2021)

Individual and household characteristics of persons with Plasmodium falciparum malaria in sites with varying endemicities in Kinshasa Province, Democratic Republic of the Congo
por: Mwandagalirwa, Melchior Kashamuka, et al.
Publicado: (2017)

Correction to: Individual and household characteristics of persons with Plasmodium falciparum malaria in sites with varying endemicities in Kinshasa Province, Democratic Republic of the Congo
por: Mwandagalirwa, Melchior Kashamuka, et al.
Publicado: (2018)

Detection of P. malariae using a new rapid isothermal amplification lateral flow assay
por: Assefa, Ashenafi, et al.
Publicado: (2023)

Effect of individual and community-level bed net usage on malaria prevalence among under-fives in the Democratic Republic of Congo
por: Levitz, Lauren, et al.
Publicado: (2018)

Epidemiology of Plasmodium malariae and Plasmodium ovale spp. in a highly malaria-endemic country: a longitudinal cohort study in Kinshasa Province, Democratic Republic of Congo
por: Sendor, Rachel, et al.
Publicado: (2023)

A deep sequencing approach to estimate Plasmodium falciparum complexity of infection (COI) and explore apical membrane antigen 1 diversity
por: Miller, Robin H., et al.
Publicado: (2017)

Association between domesticated animal ownership and Plasmodium falciparum parasite prevalence in the Democratic Republic of the Congo: a national cross-sectional study
por: Morgan, Camille E, et al.
Publicado: (2023)

Plasmodium falciparum genetic variation of var2csa in the Democratic Republic of the Congo
por: Verity, Robert, et al.
Publicado: (2018)

Spatial and epidemiological drivers of Plasmodium falciparum malaria among adults in the Democratic Republic of the Congo
por: Deutsch-Feldman, Molly, et al.
Publicado: (2020)

Epidemiology of Plasmodium malariae and Plasmodium ovale spp. in Kinshasa Province, Democratic Republic of Congo
por: Sendor, Rachel, et al.
Publicado: (2023)

Population Genetics of Plasmodium vivax in Four High Malaria Endemic Areas in Thailand
por: Congpuong, Kanungnit, et al.
Publicado: (2017)

Impact of malaria diagnostic choice on monitoring of Plasmodium falciparum prevalence estimates in the Democratic Republic of the Congo and relevance to control programs in high-burden countries
por: Diallo, Alpha Oumar, et al.
Publicado: (2023)

The impact of antimalarial resistance on the genetic structure of Plasmodium falciparum in the DRC
por: Verity, Robert, et al.
Publicado: (2020)

Impact of seasonal variations in Plasmodium falciparum malaria transmission on the surveillance of pfhrp2 gene deletions
por: Watson, Oliver John, et al.
Publicado: (2019)

Drug-Resistance and Population Structure of Plasmodium falciparum Across the Democratic Republic of Congo Using High-Throughput Molecular Inversion Probes
por: Aydemir, Ozkan, et al.
Publicado: (2018)

Population, behavioural and environmental drivers of malaria prevalence in the Democratic Republic of Congo
por: Messina, Jane P, et al.
Publicado: (2011)

Modelling the drivers of the spread of Plasmodium falciparum hrp2 gene deletions in sub-Saharan Africa
por: Watson, Oliver J, et al.
Publicado: (2017)

Low prevalence of Plasmodium malariae and Plasmodium ovale mono-infections among children in the Democratic Republic of the Congo: a population-based, cross-sectional study
por: Doctor, Stephanie M., et al.
Publicado: (2016)

The epidemiology of Plasmodium vivax among adults in the Democratic Republic of the Congo
por: Brazeau, Nicholas F., et al.
Publicado: (2021)

Impact of extractive industries on malaria prevalence in the Democratic Republic of the Congo: a population-based cross-sectional study
por: Mitchell, Cedar L., et al.
Publicado: (2022)

Reuse of malaria rapid diagnostic tests for amplicon deep sequencing to estimate Plasmodium falciparum transmission intensity in western Uganda
por: Boyce, Ross M., et al.
Publicado: (2018)

The changing landscape of Plasmodium falciparum drug resistance in the Democratic Republic of Congo
por: Deutsch-Feldman, Molly, et al.
Publicado: (2019)

The links between agriculture, Anopheles mosquitoes, and malaria risk in children younger than 5 years in the Democratic Republic of the Congo: a population-based, cross-sectional, spatial study
por: Janko, Mark M, et al.
Publicado: (2018)

A novel in vitro model reveals distinctive modulatory roles of Plasmodium falciparum and Plasmodium vivax on naïve cell-mediated immunity
por: Chitsanoor, Setthakit, et al.
Publicado: (2017)

Plasmodium falciparum is evolving to escape malaria rapid diagnostic tests in Ethiopia
por: Feleke, Sindew M., et al.
Publicado: (2021)

Low knowledge about hepatitis B prevention among pregnant women in Kinshasa, Democratic Republic of Congo
por: Thahir, Sahal, et al.
Publicado: (2022)

Plasmodium falciparum resistant to artemisinin and diagnostics have emerged in Ethiopia
por: Fola, Abebe A., et al.
Publicado: (2023)

Rapid Diagnostic Tests to Guide Case Management of and Improve Antibiotic Stewardship for Pediatric Acute Respiratory Illnesses in Resource-Constrained Settings: a Prospective Cohort Study in Southwestern Uganda
por: Ciccone, Emily J., et al.
Publicado: (2021)

Erratum for Ciccone et al., “Rapid Diagnostic Tests to Guide Case Management of and Improve Antibiotic Stewardship for Pediatric Acute Respiratory Illnesses in Resource-Constrained Settings: a Prospective Cohort Study in Southwestern Uganda”
por: Ciccone, Emily J., et al.
Publicado: (2022)

Changes in hepatitis B vaccine perception in response to the COVID-19 pandemic: Development of the Shift in vaccine confidence (SVC) survey tool
por: Boisson, Alix, et al.
Publicado: (2023)

Participant perspectives to improve tenofovir adherence in the prevention of mother-to-child transmission of hepatitis B virus in Kinshasa, DRC
por: Morgan, Camille E., et al.
Publicado: (2023)

Plasmodium falciparum sulfadoxine resistance is geographically and genetically clustered within the DR Congo
por: Taylor, Steve M., et al.
Publicado: (2013)

Similar Prevalence of Plasmodium falciparum and Non–P. falciparum Malaria Infections among Schoolchildren, Tanzania
por: Sendor, Rachel, et al.
Publicado: (2023)

A mixed methods study assessing the adoption potential of a saliva-based malaria rapid test in the Democratic Republic of Congo
por: Diaz, John, et al.
Publicado: (2023)

Streamlined, PCR-based testing for pfhrp2- and pfhrp3-negative Plasmodium falciparum
por: Parr, Jonathan B., et al.
Publicado: (2018)

Unraveling the Plasmodium vivax sporozoite transcriptional journey from mosquito vector to human host
por: Roth, Alison, et al.
Publicado: (2018)

Surveillance for sulfadoxine-pyrimethamine resistant malaria parasites in the Lake and Southern Zones, Tanzania, using pooling and next-generation sequencing
por: Ngondi, Jeremiah M., et al.
Publicado: (2017)

Arresting vertical transmission of hepatitis B virus (AVERT-HBV) in pregnant women and their neonates in the Democratic Republic of the Congo: a feasibility study
por: Thompson, Peyton, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_galg7791u3fgpb8cjlbbdfc6vj