Cargando…

FXR/TGR5 mediates inflammasome activation and host resistance to bacterial infection

Bacterial infections are a major cause of chronic infections and mortality. Innate immune control is crucial for protection against bacterial pathogens. Bile acids facilitate intestinal absorption of lipid-soluble nutrients and modulate various metabolic pathways through the farnesoid X receptor (FX...

Descripción completa

Detalles Bibliográficos
Autores principales: Kang, Ju-Hee, Kim, Minji, Yim, Mijung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8214033/
https://www.ncbi.nlm.nih.gov/pubmed/34179517
http://dx.doi.org/10.1016/j.bbrep.2021.101051