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Structural basis of KdpD histidine kinase binding to the second messenger c-di-AMP

The KdpDE two-component system regulates potassium homeostasis and virulence in various bacterial species. The KdpD histidine kinases (HK) of this system contain a universal stress protein (USP) domain which binds to the second messenger cyclic-di-adenosine monophosphate (c-di-AMP) for regulating tr...

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Detalles Bibliográficos
Autores principales: Dutta, Anirudha, Batish, Mona, Parashar, Vijay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8214093/
https://www.ncbi.nlm.nih.gov/pubmed/33989637
http://dx.doi.org/10.1016/j.jbc.2021.100771