Molecular mechanism underlying modulation of TRPV1 heat activation by polyols

Sensing noxiously high temperatures is crucial for living organisms to avoid heat-induced injury. The TRPV1 channel has long been known as a sensor for noxious heat. However, the mechanism of how this channel is activated by heat remains elusive. Here we found that a series of polyols including sucr...

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Detalles Bibliográficos
Autores principales: Nie, Yingying, Li, Yanxin, Liu, Lei, Ren, Shouyan, Tian, Yuhua, Yang, Fan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8214097/
https://www.ncbi.nlm.nih.gov/pubmed/34022223
http://dx.doi.org/10.1016/j.jbc.2021.100806

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8214097/
https://www.ncbi.nlm.nih.gov/pubmed/34022223
http://dx.doi.org/10.1016/j.jbc.2021.100806

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