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Hypoxia inducible factors regulate hepatitis B virus replication by activating the basal core promoter

BACKGROUND & AIMS: Hypoxia inducible factors (HIFs) are a hallmark of inflammation and are key regulators of hepatic immunity and metabolism, yet their role in HBV replication is poorly defined. HBV replicates in hepatocytes within the liver, a naturally hypoxic organ, however most studies of vi...

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Detalles Bibliográficos
Autores principales: Wing, Peter A.C., Liu, Peter Jianrui, Harris, James M., Magri, Andrea, Michler, Thomas, Zhuang, Xiaodong, Borrmann, Helene, Minisini, Rosalba, Frampton, Nicholas R., Wettengel, Jochen M., Mailly, Laurent, D’Arienzo, Valentina, Riedl, Tobias, Nobre, Luis, Weekes, Michael P., Pirisi, Mario, Heikenwalder, Mathias, Baumert, Thomas F., Hammond, Ester M., Mole, David R., Protzer, Ulrike, Balfe, Peter, McKeating, Jane A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8214165/
https://www.ncbi.nlm.nih.gov/pubmed/33516779
http://dx.doi.org/10.1016/j.jhep.2020.12.034