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Perm1 promotes cardiomyocyte mitochondrial biogenesis and protects against hypoxia/reoxygenation-induced damage in mice

Normal contractile function of the heart depends on a constant and reliable production of ATP by cardiomyocytes. Dysregulation of cardiac energy metabolism can result in immature heart development and disrupt the ability of the adult myocardium to adapt to stress, potentially leading to heart failur...

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Detalles Bibliográficos
Autores principales: Cho, Yoshitake, Tachibana, Shizuko, Lam, Kayla, Arita, Yoh, Khosrowjerdi, Shamim, Zhang, Oliver, Liang, Alex, Li, Ruixia, Andreyev, Aleksander, Murphy, Anne N., Ross, Robert S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8214196/
https://www.ncbi.nlm.nih.gov/pubmed/34029594
http://dx.doi.org/10.1016/j.jbc.2021.100825