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Alzheimer’s disease-associated β-amyloid does not protect against herpes simplex virus 1 infection in the mouse brain

Alzheimer’s disease (AD) is a devastating fatal neurodegenerative disease. An alternative to the amyloid cascade hypothesis is that a viral infection is key to the etiology of late-onset AD, with β-amyloid (Aβ) peptides playing a protective role. In the current study, young 5XFAD mice that overexpre...

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Detalles Bibliográficos
Autores principales: Bocharova, Olga, Pandit, Narayan P., Molesworth, Kara, Fisher, Aidan, Mychko, Olga, Makarava, Natallia, Baskakov, Ilia V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8214219/
https://www.ncbi.nlm.nih.gov/pubmed/34052228
http://dx.doi.org/10.1016/j.jbc.2021.100845