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Mitochondrial Ca(2+) oscillation induces mitophagy initiation through the PINK1-Parkin pathway

Dysregulation of the PINK1/Parkin-mediated mitophagy is essential to Parkinson’s disease. Although important progress has been made in previous researches, the biochemical reagents that induce global and significant mitochondrial damage may still hinder deeper insights into the mechanisms of mitopha...

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Detalles Bibliográficos
Autores principales: Yu, Zhengying, Wang, Haipeng, Tang, Wanyi, Wang, Shaoyang, Tian, Xiaoying, Zhu, Yujie, He, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8214625/
https://www.ncbi.nlm.nih.gov/pubmed/34148057
http://dx.doi.org/10.1038/s41419-021-03913-3