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PCGF1 promotes epigenetic activation of stemness markers and colorectal cancer stem cell enrichment

Colorectal cancer (CRC) stem cells are resistant to cancer therapy and are therefore responsible for tumour progression after conventional therapy fails. However, the molecular mechanisms underlying the maintenance of stemness are poorly understood. In this study, we identified PCGF1 as a crucial ep...

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Detalles Bibliográficos
Autores principales: Ji, Guangyu, Zhou, Wenjuan, Du, Jingyi, Zhou, Juan, Wu, Dong, Zhao, Man, Yang, Liping, Hao, Aijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8214626/
https://www.ncbi.nlm.nih.gov/pubmed/34148069
http://dx.doi.org/10.1038/s41419-021-03914-2