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Ccdc103 promotes myeloid cell proliferation and migration independent of motile cilia

The pathology of primary ciliary dyskinesia (PCD) is predominantly attributed to impairment of motile cilia. However, PCD patients also have perplexing functional defects in myeloid cells, which lack motile cilia. Here, we show that coiled-coil domain-containing protein 103 (CCDC103), one of the gen...

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Detalles Bibliográficos
Autores principales: Falkenberg, Lauren G., Beckman, Sarah A., Ravisankar, Padmapriyadarshini, Dohn, Tracy E., Waxman, Joshua S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8214733/
https://www.ncbi.nlm.nih.gov/pubmed/34028558
http://dx.doi.org/10.1242/dmm.048439