T(reg) deficiency‐mediated T(H)1 response causes human premature ovarian insufficiency through apoptosis and steroidogenesis dysfunction of granulosa cells

Immune dysregulation has long been proposed as a component of premature ovarian insufficiency (POI), but the underlying mediators and mechanisms remain largely unknown. Here we showed that patients with POI had augmented T helper 1 (T(H)1) responses and regulatory T (T(reg)) cell deficiency in both...

Descripción completa

Detalles Bibliográficos
Autores principales: Jiao, Xue, Zhang, Xiruo, Li, Nianyu, Zhang, Dunfang, Zhao, Shidou, Dang, Yujie, Zanvit, Peter, Jin, Wenwen, Chen, Zi‐Jiang, Chen, Wanjun, Qin, Yingying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8214854/
https://www.ncbi.nlm.nih.gov/pubmed/34185428
http://dx.doi.org/10.1002/ctm2.448

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8214854/
https://www.ncbi.nlm.nih.gov/pubmed/34185428
http://dx.doi.org/10.1002/ctm2.448

Ejemplares similares