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Disruption of type I interferon signaling causes sexually dimorphic dysregulation of anti-viral cytokines

Type I interferons (IFNs) play a crucial role in the establishment of an antiviral state via signaling through their cognate type I IFN receptor (IFNAR). In this study, a replication-competent but highly attenuated strain of VSV (rVSVΔm51) carrying a deletion at position 51 of the matrix protein to...

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Detalles Bibliográficos
Autores principales: Darzianiazizi, Maedeh, Allison, Katrina E., Kulkarni, Raveendra R., Sharif, Shayan, Karimi, Khalil, Bridle, Byram W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8215187/
https://www.ncbi.nlm.nih.gov/pubmed/34189454
http://dx.doi.org/10.1016/j.cytox.2021.100053