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G-quadruplex targeting chemical nucleases as a nonperturbative tool for analysis of cellular G-quadruplex DNA

G-quadruplex structures are associated with various biological activities, while in vivo evidence is essential to confirm the formation of G-quadruplexes inside cells. Most conventional agents that recognize G-quadruplex, including antibodies and small-molecule G-quadruplex ligands, either stabilize...

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Detalles Bibliográficos
Autores principales: Yu, Zhen, Hendricks, Amber L., Cowan, James A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8215219/
https://www.ncbi.nlm.nih.gov/pubmed/34189433
http://dx.doi.org/10.1016/j.isci.2021.102661