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Mitotic HOOK3 phosphorylation by ERK1c drives microtubule-dependent Golgi destabilization and fragmentation

ERK1c is an alternatively spliced isoform of ERK1 that specifically regulates mitotic Golgi fragmentation, which allows division of the Golgi during mitosis. We have previously shown that ERK1c translocates to the Golgi during mitosis where it is activated by a resident MEK1b to induce Golgi fragmen...

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Detalles Bibliográficos
Autores principales: Wortzel, Inbal, Maik-Rachline, Galia, Yadav, Suresh Singh, Hanoch, Tamar, Seger, Rony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8215223/
https://www.ncbi.nlm.nih.gov/pubmed/34189435
http://dx.doi.org/10.1016/j.isci.2021.102670