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Alteration of Membrane Cholesterol Content Plays a Key Role in Regulation of Cystic Fibrosis Transmembrane Conductance Regulator Channel Activity

Altered cholesterol homeostasis in cystic fibrosis patients has been reported, although controversy remains. As a major membrane lipid component, cholesterol modulates the function of multiple ion channels by complicated mechanisms. However, whether cholesterol directly modulates cystic fibrosis tra...

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Detalles Bibliográficos
Autores principales: Cui, Guiying, Cottrill, Kirsten A., Strickland, Kerry M., Mashburn, Sarah A., Koval, Michael, McCarty, Nael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8215275/
https://www.ncbi.nlm.nih.gov/pubmed/34163370
http://dx.doi.org/10.3389/fphys.2021.652513