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Alteration of Membrane Cholesterol Content Plays a Key Role in Regulation of Cystic Fibrosis Transmembrane Conductance Regulator Channel Activity
Altered cholesterol homeostasis in cystic fibrosis patients has been reported, although controversy remains. As a major membrane lipid component, cholesterol modulates the function of multiple ion channels by complicated mechanisms. However, whether cholesterol directly modulates cystic fibrosis tra...
Autores principales: | Cui, Guiying, Cottrill, Kirsten A., Strickland, Kerry M., Mashburn, Sarah A., Koval, Michael, McCarty, Nael A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8215275/ https://www.ncbi.nlm.nih.gov/pubmed/34163370 http://dx.doi.org/10.3389/fphys.2021.652513 |
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