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Protocol for the preparation of site-specific succinylated histone mimics to investigate the impact on nucleosome dynamics

Lysine succinylation is a recently discovered posttranslational modification that plays critical roles in metabolism, epigenetic signaling, and human diseases. To investigate the effects of site-specific histone lysine succinylation on nucleosome dynamics requires the generation of homogeneously mod...

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Detalles Bibliográficos
Autores principales: Jing, Yihang, Liu, Zheng, Li, Xiang David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8215284/
https://www.ncbi.nlm.nih.gov/pubmed/34189470
http://dx.doi.org/10.1016/j.xpro.2021.100604