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Protocol for the preparation of site-specific succinylated histone mimics to investigate the impact on nucleosome dynamics
Lysine succinylation is a recently discovered posttranslational modification that plays critical roles in metabolism, epigenetic signaling, and human diseases. To investigate the effects of site-specific histone lysine succinylation on nucleosome dynamics requires the generation of homogeneously mod...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8215284/ https://www.ncbi.nlm.nih.gov/pubmed/34189470 http://dx.doi.org/10.1016/j.xpro.2021.100604 |