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Structural and functional insights into aldosterone synthase interaction with its redox partner protein adrenodoxin
Aldosterone is the major mineralocorticoid in the human body controlling blood pressure and salt homeostasis. Overproduction of aldosterone leads to primary aldosteronism, which is the most common form of secondary hypertension with limited treatment options. Production of aldosterone by cytochrome...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8215293/ https://www.ncbi.nlm.nih.gov/pubmed/34015331 http://dx.doi.org/10.1016/j.jbc.2021.100794 |