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Sodium Thiosulfate Improves Intestinal and Hepatic Microcirculation Without Affecting Mitochondrial Function in Experimental Sepsis

INTRODUCTION: In the immunology of sepsis microcirculatory and mitochondrial dysfunction in the gastrointestinal system are important contributors to mortality. Hydrogen sulfide (H(2)S) optimizes gastrointestinal oxygen supply and mitochondrial respiration predominantly via K(ATP)-channels. Therefor...

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Detalles Bibliográficos
Autores principales: Schulz, Jan, Kramer, Sandra, Kanatli, Yasin, Kuebart, Anne, Bauer, Inge, Picker, Olaf, Vollmer, Christian, Truse, Richard, Herminghaus, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8215355/
https://www.ncbi.nlm.nih.gov/pubmed/34163476
http://dx.doi.org/10.3389/fimmu.2021.671935