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Cefdinir and β-Lactamase Inhibitor Independent Efficacy Against Mycobacterium tuberculosis

Background: There is renewed interest in repurposing β-lactam antibiotics for treatment of tuberculosis (TB). We investigated efficacy of cefdinir, that withstand the β-lactamase enzyme present in many bacteria, against drug-susceptible and multi-drug resistant (MDR) Mycobacterium tuberculosis (Mtb)...

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Detalles Bibliográficos
Autores principales: Srivastava, Shashikant, Thomas, Tania, Howe, Dave, Malinga, Lesibana, Raj, Prithvi, Alffenaar, Jan-Willem, Gumbo, Tawanda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8215380/
https://www.ncbi.nlm.nih.gov/pubmed/34163361
http://dx.doi.org/10.3389/fphar.2021.677005