The Role of B Cells in Primary Progressive Multiple Sclerosis

The success of ocrelizumab in reducing confirmed disability accumulation in primary progressive multiple sclerosis (PPMS) via CD20-targeted depletion implicates B cells as causal agents in the pathogenesis of PPMS. This review explores the possible mechanisms by which B cells contribute to disease p...

Descripción completa

Detalles Bibliográficos
Autores principales: Holloman, Jameson P., Axtell, Robert C., Monson, Nancy L., Wu, Gregory F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Neurology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8215437/
https://www.ncbi.nlm.nih.gov/pubmed/34163430
http://dx.doi.org/10.3389/fneur.2021.680581

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8215437/
https://www.ncbi.nlm.nih.gov/pubmed/34163430
http://dx.doi.org/10.3389/fneur.2021.680581

Ejemplares similares