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Hyperactivation of monocytes and macrophages in MCI patients contributes to the progression of Alzheimer's disease

BACKGROUND: Alzheimer’s disease (AD) is the most common neurodegenerative disease ultimately manifesting as clinical dementia. Despite considerable effort and ample experimental data, the role of neuroinflammation related to systemic inflammation is still unsettled. While the implication of microgli...

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Detalles Bibliográficos
Autores principales: Munawara, Usma, Catanzaro, Michael, Xu, Weili, Tan, Crystal, Hirokawa, Katsuiku, Bosco, Nabil, Dumoulin, David, Khalil, Abdelouahed, Larbi, Anis, Lévesque, Simon, Ramassamy, Charles, Barron, Annelise E., Cunnane, Stephen, Beauregard, Pascale B., Bellenger, Jean-Pierre, Rodrigues, Serafim, Desroches, Mathieu, Witkowski, Jacek M., Laurent, Benoit, Frost, Eric H., Fulop, Tamas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8215492/
https://www.ncbi.nlm.nih.gov/pubmed/34154615
http://dx.doi.org/10.1186/s12979-021-00236-x