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Intra-Herb Interactions: Primary Metabolites in Coptidis Rhizoma Extract Improved the Pharmacokinetics of Oral Berberine Hydrochloride in Mice

Primary plant metabolites can be used for artificial preparation of natural deep eutectic solvents (NADESs), which have strong dissolving capacity, good biocompatibility, and biodegradability. In this study, for the first time, we verified that NADESs were present in Coptidis Rhizoma extract and sys...

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Detalles Bibliográficos
Autores principales: Zhao, Jing, Zhou, Ting, Lu, Jing-Ze, Ye, Dan, Mu, Sheng, Tian, Xin-Hui, Zhang, Wei-Dong, Ma, Bing-Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8215677/
https://www.ncbi.nlm.nih.gov/pubmed/34163360
http://dx.doi.org/10.3389/fphar.2021.675368