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Regulated Intramembrane Proteolysis of ACE2: A Potential Mechanism Contributing to COVID-19 Pathogenesis?

Since being identified as a key receptor for SARS-CoV-2, Angiotensin converting enzyme 2 (ACE2) has been studied as one of the potential targets for the development of preventative and/or treatment options. Tissue expression of ACE2 and the amino acids interacting with the spike protein of SARS-CoV-...

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Detalles Bibliográficos
Autores principales: Gonzalez, Sandra M., Siddik, Abu Bakar, Su, Ruey-Chyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8215698/
https://www.ncbi.nlm.nih.gov/pubmed/34163462
http://dx.doi.org/10.3389/fimmu.2021.612807