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A 8-mer Peptide of PGLYRP1/Tag7 Innate Immunity Protein Binds to TNFR1 Receptor and Inhibits TNFα-Induced Cytotoxic Effect and Inflammation

Search for novel regulatory protein fragments with potential functional roles is required both for understanding the immune response mechanisms and the development of targeted immunotherapy. Earlier we demonstrated that the PGLYRP1/Tag7 innate immunity protein can be regarded as an inhibitor of TNFα...

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Detalles Bibliográficos
Autores principales: Telegin, Georgii B., Chernov, Aleksandr S., Kazakov, Vitaly A., Romanova, Elena A., Sharapova, Tatiana N., Yashin, Denis V., Gabibov, Alexander G., Sashchenko, Lidia P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8215708/
https://www.ncbi.nlm.nih.gov/pubmed/34163464
http://dx.doi.org/10.3389/fimmu.2021.622471