RNA-binding protein IMP3 is a novel regulator of MEK1/ERK signaling pathway in the progression of colorectal Cancer through the stabilization of MEKK1 mRNA

BACKGROUND: MEK1/ERK signaling pathway plays an important role in most tumor progression, including colorectal cancer (CRC), however, MEK1-targeting therapy has little effective in treating CRC patients, indicating there may be a complex mechanism to activate MEK1/ERK signaling pathway except RAS ac...

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Detalles Bibliográficos
Autores principales: Zhang, Meng, Zhao, Senlin, Tan, Cong, Gu, Yanzi, He, Xuefeng, Du, Xiang, Li, Dawei, Wei, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8215736/
https://www.ncbi.nlm.nih.gov/pubmed/34154626
http://dx.doi.org/10.1186/s13046-021-01994-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8215736/
https://www.ncbi.nlm.nih.gov/pubmed/34154626
http://dx.doi.org/10.1186/s13046-021-01994-8

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